Drug Development and Research

Continuous progress in drug development and research field is necessary for invention of new drugs and drug targets for STDs. Identification of the drug target is the basis of the drug development process, this can be done through various computational approaches. HIV drug targets different steps in life cycle of the virus as it infects CD4 T-lymphocytes or another target cell. Gene editing technology such as CRISPR seeks to eliminate the latent as well active HIV infection in the human which would be more effective in the treatment of AIDS. Various viral inhibitors such as entry inhibitors, maturation inhibitors are designed to inhibit the replication of the virus inside the host cell.

  • Track 1-1 Nucleoside reverse transcriptase inhibitors (NRTIs)
  • Track 2-2 Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
  • Track 3-3 Protease inhibitors (PIs)
  • Track 4-4 Integrase inhibitors (INSTIs)
  • Track 5-5 Fusion inhibitors (FIs)
  • Track 6-6 Chemokine receptor antagonists (CCR5 antagonists)
  • Track 7-7 Entry inhibitors (CD4-directed post-attachment inhibitors)
  • Track 8-8 Therapeutic Vaccination Development
  • Track 9-9 Gene Editing Technology

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